Systems Biology and Drug Discovery
* 일 시 : 2010년 2월 9일(화) 오전 10:00 - 오후 5:30
* 장 소 : 연세대학교 연세-삼성 학술정보원 장기원국제회의실 (6층)
* 주 관 : 연세대학교 Global 5-5-10 시스템생물학사업단
* 후 원 : 연세대학교 단백질기능제어 이행 연구센터(ERC), 연세대학교 생체분자기능사업단(BK21)
Program
10:00 - 10:10 : Opening Remark
Chul Soo Shin (Director, Global 5-5-10 Systems Biology Initiative)
Plenary Lecture 1
10:10 - 10:50 Sang Chul Park (Seoul National University, Korea)
“A new insight into the mechanism of aging for growth arrest and apoptosis resistance: nuclear barrier hypothesis of aging”
Session 1 : Systems Biology on Aging
Chair : In Kwon Chung (Professor, Department of Biology, Yonsei University)
10:50 - 11:20 Yong-Keun Jung (Seoul National University, Korea)
“Role of Autophagy in the Modulation of Lifespan and Tauopathy”
11:20 - 11:50 Jae-Yong Lee (Hallym University, College of Medicine, Korea)
“Role of FOXO3a on regulation of ROS and DNA repair in aging”
11:50 - 12:20 Katsuyoshi Mihara (University of Kyushu, Japan)
“The physiological importance of mammalian mitochondrial fission factor Drp1”
12:20 - 13:20 Lunch
Plenary Lecture 2
13:20-14:00 Ruben Abagyan (University of california, USA)
“Challenges in Structure Based Chemogenomics and Drug Discovery”
Session 2 : Drug Discovery and its Clinical Application
Chair : Kyoung Tai No (Professor, Department of Biotechnology, Yonsei University)
14:00 - 14:30 Soon Kil Ahn (University of Incheon, Korea)
“From Discovery to Clinical Trials of Anti-Diabetic Drug”
14:30 - 15:00 Yong Zu Kim (LegoChemBio, Korea)
“New Oxazolidinones with Cyclic Amidrazone : Structure-Activity Relationship of Cyclic Amidrazone Oxazolidinones”
15:00 - 15:30 Yasuteru Urano (University of Tokyo, Japan)
“Rational design of novel fluorescence probes for visualizing various cellular responses and in vivo tumor imaging”
15:30 - 15:50 Coffee Break
Session 3 : Systems Biology on Stem Cell
Chair : Sung Kil Lim (Professor, Yonsei University College of Medicine)
15:50 - 16:20 Riko Nishimura (University of Osaka, Japan)
“Regulation of differentiation program of mesenchymal stem cells by transcription factors”
16:20 - 16:50 Jin Woo Lee (Yonsei University, College of Medicine, Korea)
“Transcriptional regulation of mesenchymal stem cell differentiation”
16:50 - 17:20 Hiroshi Kawaguchi (University of Tokyo, Japan)
“Therapeutic Target Molecules for Cartilage Degradation in Osteoarthritis”
17:20 - 17:25 Concluding Remark
Chul Soo Shin (Director, Global 5-5-10 Systems Biology Initiative)
