Please give a lot of attention and participation from the members of the Mechanical Engineering department.

▣ Title: Development of Degradable Hydrogels and Hydrogel-based Biosensors

▣ Speaker: 신동식 교수

▣ Affiliation: 숙명여자대학교 화공생명공학부

▣ Date: 2025. 12. 12.(Fri) 17:00

▣ Venue: 제4공학관 D404호

▣ Abstract

The goal of this work is to develop “smart materials for tissue engineering and biosensors” in combination with Micro-Electro-Mechanical Systems (MEMS) technology. In the first part of the work, a method for capture, analysis, and sorting of live cells using a photodegradable hydrogel (photogel) functionalized with antibodies will be demonstrated. Photogel substrates were used to isolate human CD4 or CD8 T-cells from a heterogeneous cell suspension and then to release desired cells or groups of cells by UV-induced photodegradation.  As the second part of the work, biomarkers related with diseases including proteases and nitrite ions were detected by using hydrogel-based biosensors. This method will be providing numerous real time secretion profiles rather than conventional detection methods including ELISA, PCR and gel electrophoresis.